DemodexFolliculitis Mimicking Acute Graft-vs-Host Disease
نویسندگان
چکیده
منابع مشابه
Acute graft versus host disease
Acute graft-versus-host disease (GVHD) occurs after allogeneic hematopoietic stem cell transplant and is a reaction of donor immune cells against host tissues. Activated donor T cells damage host epithelial cells after an inflammatory cascade that begins with the preparative regimen. About 35%-50% of hematopoietic stem cell transplant (HSCT) recipients will develop acute GVHD. The exact risk is...
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Graft-versus-host disease (GVHD) has been the primary limitation to the wider application of allogeneic bone marrow transplantation (BMT). The immunobiology of acute GVHD is complex and can be conceptualized to be a three-step process. In step 1, the conditioning regimen (irradiation and/or chemotherapy) leads to the damage and activation of host tissues and induces the secretion of inflammator...
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Received August 1, 2013, Revised September 30, 2013, Accepted for publication October 21, 2013 Corresponding author: Jun Young Lee, Department of Dermatology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701, Korea. Tel: 82-2-2258-1386, Fax: 82-2-599-9950, E-mail: [email protected] This is an Open Access article distr...
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AIMS Animal studies have shown that antigens present within the gut play an important role in the development of acute graft versus host disease (GvHD) following allogeneic bone marrow transplantation (BMT). In previous studies, inert sugars have been found to penetrate the small bowel mucosa after conditioning therapy for BMT; endotoxaemia can also occur during acute GvHD. Data on absorption o...
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ژورنال
عنوان ژورنال: JAMA Dermatology
سال: 2013
ISSN: 2168-6068
DOI: 10.1001/jamadermatol.2013.5891